Details
Quality products?make an important contribution to long-term revenue and profitability. Quality Factory Supply 99% Pure Verapamil 52-53-9 with Efficient Delivery
1.What is the Verapamil ?
Verapamil is used for preventing angina pectoris attacks, arterial hypertension, and treating and preventing supraventricular arrhythmia (paroxysmal supraventricular tachycardia, atrial fibrillation, atrial flutter, extrasystole).
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871703-17-2
2-(3,4-dimethoxyphenyl)-2-(2-[1,3]dioxolan-2-yl-ethyl)-3-methyl-butyronitrile
-
-
3490-06-0
N-methylhomoveratrylamine
-
-
52-53-9,56949-77-0
Verapamil
| Conditions | Yield |
|---|---|
|
With
formic acid;
palladium on activated charcoal;
In
ethanol;
at 100 ℃;
for 18h;
|
83% |
-
-
3490-06-0
N-methylhomoveratrylamine
-
isopropanolic HCl
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isopropanolic HCl
-
-
102201-30-9
4-(3 4-dimethoxyphenyl)-4-cyano-5-methylcapronitrile
-
-
52-53-9,56949-77-0
Verapamil
| Conditions | Yield |
|---|---|
|
With
hydrogen;
palladium-carbon;
In
ethyl acetate; isopropyl alcohol;
|
2.What is the CAS number for Verapamil ?
The CAS number of Verapamil is 52-53-9.
More information of Verapamil 52-53-9 are:
|
CAS?Number |
52-53-9 |
|
Density |
1.058 g/cm3 |
|
Melting Point |
25°C |
|
Boiling Point |
586.1 °C at 760 mmHg |
|
Flash Point |
308.3 °C |
|
Refractive Index |
1.5448 |
|
PSA |
63.95000 |
|
LogP |
5.09308 |
|
Pka |
8.6(at 25℃) |
3.What are another words for Verapamil ?
Synonyms?for?Verapamil 52-53-9:Valeronitrile,5-[(3,4-dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropyl-(7CI,8CI);5-[(3,4-Dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile;CP 16533-1;Lekoptin;Iproveratril;D 365;R,S-Verapamil;NSC 272306NA;VPL;dl-Verapamil;
4.What is the molecular formula of Verapamil?
The chemical formula of ?Verapamil is?C27H38N2O4 which containing 27 Carbon atoms,38 Hydrogen atoms,2 Nitrogen atoms and 4 Oxygen atoms,and the molecular weight of??Verapamil?is 454.61.
5.What is Verapamil (52-53-9) used for?
Verapamil is a synthetic, tertiary amino compound with a chemical structure that exhibits slight structural similarity to papaverine. It is characterized by its ability to rapidly absorb after oral administration and undergo quick metabolism, resulting in low bioavailability. The drug is known for its effects on hemodynamics, including changes in preload, afterload, contractility, heart rate, and coronary blood flow. Verapamil is primarily composed of a levorotatory enantiomer, which is the most potent form. The drug is metabolized in the liver, with the main metabolic step being N-dealkylation, followed by O-demethylation and subsequent conjugation before elimination. The metabolites produced have no significant biological activity, and Verapamil has an elimination half-life of approximately 5 hours.
InChI:InChI=1/C27H37N2O4/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6/h9-12,17-18,20H,7-8,13-16H2,1-6H3
Relevant articles related to Verapamil:
|
Article |
Source |
|
Floating pharmaceutical composition comprising an active phase and a non-active phase |
- , (2010/04/23) |
|
ANTIHYPERTENSIVE THERAPY |
- , (2009/09/08) |
6.Buy Verapamil with the best price .
Zhuhai Wangji Technology Co.,Ltd is a quality supplier of Verapamil. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Verapamil 52-53-9.
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